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Article

HLA-DQA1*04:01 is related to a higher multiple sclerosis lesion load on T2/Flair MRI sequences.

Arquivos de neuro-psiquiatria - 1 Dec 2021

Noro Fabio, Alves-Leon Soniza Vieira, Fontes-Dantas Fabricia Lima, Valle Bahia Paulo Roberto, Andreiuolo Rodrigo Ferrone, Rueda Lopes Fernanda Cristina, Pereira Valeria Coelho Santa Rita, Abi-Haila Livia de Almeida Afonso, Coutinho Renan Amaral, Araujo Amanda Dutra de, Marchiori Edson

Abstract excerpt

BACKGROUND: The genetic predisposition to multiple sclerosis (MS) is associated with HLA alleles, especially HLA-DRB1*15:01. OBJECTIVE: To identify associations between findings in magnetic resonance imaging (MRI) and genetic features in a Brazilian cohort of patients with MS. METHODS: We retrospectively studied data from 95 consecutive patients with MS. Two independent observers who were blinded to the clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34877984
DOI: 10.1590/0004-282X-ANP-2020-0487

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