Article

Endothelial mechanobiology under controlled disturbed flows

2023-08-28

Abstract excerpt

Early atherosclerotic lesions often develop in areas of disturbed flow within arterial curvatures and bifurcations. Complex flows alter the signaling of inflammatory and other signaling molecules that may exacerbate the disease phenotype. Microfluidic platforms to assess changes in endothelial mechanobiology generally employ laminar unidirectional or oscillatory flows generated in straight channels; such platforms...

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Literature Corpus work: 3eb1adb9-8df8-5ae1-8c8c-20398fb24bd0
DOI: 10.1101/2023.08.27.555040

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