Article
Flow-mediated signaling modulates endothelial cell phenotype.
Endothelium : journal of endothelial cell research - 1 Jan 2000
Garin Gwenaele, Berk Bradford C
Abstract excerpt
The focal development of atherosclerosis in the vascular tree may be explained in part by the local nature of blood flow. Bifurcations and branching points, prone to early atherogenesis, experience disturbed and oscillatory flow, whereas straight vascular regions, resistant to atherosclerosis, are exposed to steady laminar flow. A large number of studies suggest that the antiatherosclerotic effects of laminar...
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