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Article

Genetic profile of the arylamine N-acetyltransferase 2 coding gene among individuals from two different regions of Brazil.

Mutation research - 1 Nov 2007

Teixeira Raquel L F, Miranda Antonio B, Pacheco Antonio G, Lopes Márcia Q P, Fonseca-Costa Joseane, Rabahi Marcelo F, Melo Hedi M, Kritski Afrânio L, Mello Fernanda C Q, Suffys Philip N, Santos Adalberto R

Abstract excerpt

Arylamine N-acetyltranferase 2 is the main enzyme responsible for the isoniazid metabolization into hepatotoxic intermediates and the degree of hepatotoxicity severity has been attributed to genetic variability in the NAT2 gene. The main goal of this study was to describe the genetic profile of the NAT2 gene in individuals from two different regions of Brazil: Rio de Janeiro and Goiás States. Therefore, after...

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Source

Identifiers

PMID: 17509624
DOI: 10.1016/j.mrfmmm.2007.03.015

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic profile of the arylamine N-acetyltransferase 2 coding gene among individuals from two different regions of Brazil.PMID 17509624Read ↗

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Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population.Semantic proximity Read ↗

Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients.Semantic proximity Read ↗

Study of NAT2 gene polymorphisms in an Indian population: association with plasma isoniazid concentration in a cohort of tuberculosis patients.Semantic proximity Read ↗

Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.Semantic proximity Read ↗

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