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Article

The distribution of allelic and genotypic frequencies of N-Acetyltransferase-2 variants in an Argentine population.

Journal of infection in developing countries - 17 Sept 2012

Chamorro Julián Gabriel, Castagnino Jorge P, Musella Rosa M, Frias Ana, Aranda Federico Manuel, De Larrañaga Gabriela Fernanda

Abstract excerpt

INTRODUCTION: Arylamine N-acetyltransferase-2 (NAT-2) is a key human enzyme in drug detoxification and elimination. Mutations in NAT-2 affect the activity of anti-tuberculosis drugs and result in three different phenotypes: rapid (RA), intermediate (IA) and slow acetylators (SA). METHODOLOGY: The allelic, genotypic and phenotypic frequencies of NAT-2 were studied in 185 patients from Buenos Aires by restriction...

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Identifiers

PMID: 23000867
DOI: 10.3855/jidc.2111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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