Article
A study of N-acetyltransferase 2 gene polymorphisms in the Indian population and its relationship with serum isoniazid concentrations in a cohort of tuberculosis patients.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace - 31 Dec 2025
Munshi Renuka, Panchal Falguni, Desai Unnati, Utpat Ketaki, Rajoria Kirti
Abstract excerpt
The N-acetyltransferase 2 (NAT2) gene exhibits substantial genetic diversity, leading to distinct acetylator phenotypes among individuals. In this study, we determine NAT2 gene polymorphisms in tuberculosis (TB) patients and analyze serum isoniazid (INH) concentrations across the various genotypes. An observational prospective cohort study involving 217 patients with pulmonary or extrapulmonary TB was carried...
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