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Article

Genotype and allele frequencies of isoniazid-metabolizing enzymes NAT2 and GSTM1 in Latvian tuberculosis patients.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Jul 2016

Igumnova Viktorija, Capligina Valentina, Krams Alvils, Cirule Andra, Elferts Didzis, Pole Ilva, Jansone Inta, Bandere Dace, Ranka Renate

Abstract excerpt

Pharmacogenomic testing of tuberculosis drug-metabolizing enzyme genes was proposed as a strategy to identify patients at risk for suboptimal responses to medications. However, variations of the genotype frequencies among ethnic groups exist and new alleles are been identified. The aim of this study was to identify polymorphisms of genes encoding metabolic enzymes NAT2 and GSTM1 in tuberculosis patients in Latvia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27236516
DOI: 10.1016/j.jiac.2016.04.003

Genes

NAT2
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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