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Article

Study of NAT2 gene polymorphisms in an Indian population: association with plasma isoniazid concentration in a cohort of tuberculosis patients.

Molecular diagnosis & therapy - 1 Jan 2009

Singh Neera, Dubey Sudhisha, Chinnaraj Saravanan, Golani Anil, Maitra Anurupa

Abstract excerpt

BACKGROUND AND OBJECTIVES: Polymorphisms of the N-acetyltransferase 2 gene (NAT2) vary remarkably between populations of different ethnic origin. The NAT2 gene determines the individual's acetylator status to metabolize drugs and xenobiotics, influencing their toxicity and efficacy profiles. This study investigates the frequencies of the most commonly studied NAT2 polymorphisms in a southwestern Indian population...

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Topics

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Share to Acetylation
Share to Amplified Fragment Length Polymorphism Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antitubercular Agents

Share to Arylamine N-Acetyltransferase

Share to Inactivation, Metabolic

Share to Isoniazid

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 19351215
DOI: 10.1007/BF03256314

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Study of NAT2 gene polymorphisms in an Indian population: association with plasma isoniazid concentration in a cohort of tuberculosis patients.PMID 19351215Read ↗

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