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Article

Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients.

Molecular genetics & genomic medicine - 1 Oct 2021

Levano Kelly S, Jaramillo-Valverde Luis, Tarazona David D, Sanchez Cesar, Capristano Silvia, Vásquez-Loarte Tania, Solari Lely, Mendoza-Ticona Alberto, Soto Alonso, Rojas Christian, Zegarra-Chapoñan Roberto, Guio Heinner

Abstract excerpt

BACKGROUND: We determined the frequency of genetic polymorphisms in three anti-TB drug metabolic proteins previously reported: N-acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1), and arylacetamide deacetylase (AADAC) within a Peruvian population in a cohort of TB patients. METHODS: We genotyped SNPs rs1041983, rs1801280, rs1799929, rs1799930, rs1208, and for NAT2; and for...

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Share to Arylamine N-Acetyltransferase
Share to Carboxylic Ester Hydrolases
Share to Cytochrome P-450 CYP2E1
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Identifiers

PMID: 34510815
DOI: 10.1002/mgg3.1764
PMCID: PMC8580101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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