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Allelic and Genotypic Frequencies of NAT2, CYP2E1 and AADAC genes in a cohort of Peruvian Tuberculosis Patients

2021-02-28

Abstract excerpt

<h4>Background</h4> We determined the frequency of genetic polymorphisms in three anti-TB drug metabolic proteins previously reported: N-acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1) and arylacetamide deacetylase (AADAC) within a Peruvian population in a cohort of TB patients. We included 395 participants completed their anti-tuberculosis treatment. <h4>Results</h4> ∼74% of the participants are carrie...

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Literature Corpus work
963b9bbe-54d4-5774-a84c-f91a65fa7e00
DOI
10.1101/2021.02.27.433209
Open publication

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Allelic and Genotypic Frequencies of NAT2, CYP2E1 and AADAC genes in a cohort of Peruvian Tuberculosis PatientsDOI 10.1101/2021.02.27.433209
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