Article
Development of a novel microarray methodology for the study of SNPs in the promoter region of the TNF-alpha gene: their association with obstructive pulmonary disease in Greek patients.
Clinical biochemistry - 1 Aug 2007
Papatheodorou Athanasios, Latsi Panagiota, Vrettou Christina, Dimakou Aikaterini, Chroneou Alexia, Makrythanasis Periklis, Kaliakatsos Marios, Orfanidou Dora, Roussos Charis, Kanavakis Emmanuel, Tzetis Maria
Abstract excerpt
OBJECTIVES: Polymorphisms in promoter region of TNF-alpha gene were shown to interfere with the transcriptional activity of the gene resulting in the production of different levels of TNF-alpha product suggesting their involvement in susceptibility or severity of many inflammatory diseases. We se...
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