Article
Functional study of TNF-α promoter polymorphisms: literature review and meta-analysis.
European cytokine network - 1 Jun 2011
Mekinian Arsene, Tamouza Ryad, Pavy Stephan, Gestermann Nicolas, Ittah Marc, Mariette Xavier, Miceli-Richard Corinne
Abstract excerpt
The functional consequences of TNF-α promoter SNPs are still controversial and, to date, the functional consequences of TNF-α haplotype combinations in healthy subjects have not been assessed. In order to assess functional consequences of each TNF-α polymorphism and of their haplotype combination, TNF-α expression and secretion by LPS-stimulated monocytes from 50 healthy subjects were assessed. Monocytes were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.