Article
Development of novel microarray methodology for the study of mutations in the SERPINA1 and ADRB2 genes--their association with Obstructive Pulmonary Disease and Disseminated Bronchiectasis in Greek patients.
Clinical biochemistry - 1 Jan 2010
Papatheodorou Athanasios, Makrythanasis Periklis, Kaliakatsos Marios, Dimakou Aikaterini, Orfanidou Dora, Roussos Charis, Kanavakis Emmanuel, Tzetis Maria
Abstract excerpt
OBJECTIVES: The aim of our study was to determine the genetic risk conferred by SNPs in the SERPINA1 and ADRB2 for development of Chronic Obstructive Pulmonary Disease (COPD) and Disseminated Bronchiectasis (DB), while at the same time validating the NanoChip technology. This was a case-control study consisting of 112 COPD, 62 DB patients and 2 control groups (106 smokers without COPD: healthy smokers control...
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