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Article

Role and pharmacogenomics of TNF-alpha in asthma.

Mini reviews in medicinal chemistry - 1 Aug 2008

Lykouras Dimosthenis, Sampsonas Fotis, Kaparianos Alexandros, Karkoulias Kiriakos, Spiropoulos Kostas

Abstract excerpt

Asthma is a chronic heterogeneous inflammatory disease of the respiratory system in which numerous cytokines play a significant role. Among them TNF-alpha (tumour necrosis factor alpha), a proinflammatory cytokine, has a predominant role in orchestrating airway inflammation and affecting treatment outcome. In this review we attempt to summarize the involvement of TNF-alpha in the pathogenesis of asthma,...

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Source

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PMID: 18691151
DOI: 10.2174/138955708785132828

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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