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Article

Association of TNF-alpha polymorphism with susceptibility to and severity of non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2006

Shih Chuen-Ming, Lee Yao-Ling, Chiou Hui-Ling, Chen Wei, Chang Gee-Chen, Chou Ming-Chih, Lin Long-Yau

Abstract excerpt

BACKGROUND: Genetic polymorphisms in the promoter region of the tumor necrosis factor-alpha (TNF-alpha) gene are involved in the regulation of expression levels and have been associated with various inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter region of the TNF-alpha gene (-308 G/A and -238 G/A) for their role in the susceptibility to and severity of non-small cell...

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Source

Identifiers

PMID: 16476505
DOI: 10.1016/j.lungcan.2005.11.011

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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