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Article

Identification of genetic variants in the TNF promoter associated with COPD secondary to tobacco smoking and its severity.

International journal of chronic obstructive pulmonary disease - 1 Jan 2015

Reséndiz-Hernández Juan Manuel, Sansores Raúl H, Hernández-Zenteno Rafael de Jesús, Vargas-Alarcón Gilber, Colín-Barenque Laura, Velázquez-Uncal Mónica, Camarena Angel, Ramírez-Venegas Alejandra, Falfán-Valencia Ramcés

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is an inflammatory disease that arises in response to noxious particles or gases. Associations of genetic polymorphisms in TNF have been reported in Asians and Caucasians, but not in Mestizo populations. A case-control study was conducted in two stages: in the first stage, patients with COPD (COPD group, n=165) and smokers without disease (SNC group, n=165) were...

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Identifiers

PMID: 26170653
DOI: 10.2147/COPD.S83298
PMCID: PMC4493967

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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