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Article

Comparison of mass spectrometric analysis and TRUGENE HBV genotyping for monitoring lamivudine resistance in chronic hepatitis B patients.

Antiviral therapy - 1 Jan 2007

Woo Hee-Yeon, Park Hyosoon, Kim Byung-Ik, Jeon Woo-Kyu, Cho Yong Kyun, Kim Young Jae

Abstract excerpt

BACKGROUND: There is an increasing need for the early detection of emerging mutations in the tyrosine-methionine-aspartate-aspartate (YMDD) motif of hepatitis B virus (HBV) DNA polymerase with using sensitive molecular methods. METHODS: We evaluated the usefulness of monitoring lamivudine resistance using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based assay (the restriction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17503742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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