Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of hepatitis B virus YMDD variants using mass spectrometric analysis of oligonucleotide fragments.

Journal of hepatology - 1 May 2004

Hong Sun Pyo, Kim Nam Keun, Hwang Seong Gyu, Chung Hyun Jae, Kim Sukjoon, Han Jin Hee, Kim Hyung Tae, Rim Kyu Sung, Kang Myung Seo, Yoo Wangdon, Kim Soo-Ok

Abstract excerpt

BACKGROUND/AIMS: Mutations in hepatitis B virus (HBV) to lamivudine resistance that arise during prolonged treatment frequently cause amino acid substitutions in the YMDD motif of HBV DNA polymerase. Current methods of detecting such variants are time-consuming, labor intensive, and unsuitable fo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Antiviral Agents
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Lamivudine

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 15094233
DOI: 10.1016/j.jhep.2004.01.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15094233-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of hepatitis B virus YMDD variants using mass spectrometric analysis of oligonucleotide fragments.PMID 15094233Read ↗

Multiplex detection of 60 hepatitis B virus variants by maldi-tof mass spectrometry.Semantic proximity Read ↗

Application of mass spectrometry to molecular surveillance of hepatitis B and C viral infections.Semantic proximity Read ↗

Comparison of mass spectrometric analysis and TRUGENE HBV genotyping for monitoring lamivudine resistance in chronic hepatitis B patients.Semantic proximity Read ↗

[Detection and identification of HBV DNA YMDD motif mutation during lamivudine treatment using oligonucleotide array].Semantic proximity Read ↗

Rapid detection of the hepatitis B virus YMDD mutant using AllGlo™ probes.Semantic proximity Read ↗

Predominance of hepatitis B virus YMDD mutants is prognostic of viral DNA breakthrough.Semantic proximity Read ↗

Robust hepatitis B virus genotyping by mass spectrometry.Semantic proximity Read ↗

Population Genotyping of Hepatitis C Virus by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Short DNA FragmentsSemantic proximity Read ↗

[Detection of YMDD motif mutations in lamivudine-untreated patients with chronic hepatitis B].Semantic proximity Read ↗

Hepatitis B virus quantification and detection of YMDD mutants in a single reaction by real-time PCR and annealing curve analysis.Semantic proximity Read ↗

Detection of YMDD mutation using mutant-specific primers in chronic hepatitis B patients before and after lamivudine treatment.Semantic proximity Read ↗

Detection of YMDD mutants using universal template real-time PCR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.