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Article

Predominance of hepatitis B virus YMDD mutants is prognostic of viral DNA breakthrough.

Gastroenterology - 1 Apr 2006

Lee Chang Hong, Kim Soo-Ok, Byun Kwan Soo, Moon Myung Soon, Kim Eun-Ok, Yeon Jong Eun, Yoo Wangdon, Hong Sun Pyo

Abstract excerpt

BACKGROUND & AIMS: Hepatitis B virus (HBV) tyrosine, methionine, aspartate, aspartate (YMDD) mutants with or without additional compensatory mutations occur in chronically infected patients during lamivudine therapy and may be associated with accompanying viral breakthrough. The aim of this study was to determine whether a predominance of YMDD mutants could be a prognostic marker for occurrence of viral DNA...

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Share to DNA, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Reverse Transcriptase Inhibitors

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Identifiers

PMID: 16618409
DOI: 10.1053/j.gastro.2006.01.005

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