Article
Application of mass spectrometry to molecular surveillance of hepatitis B and C viral infections.
Antiviral therapy - 1 Jan 2012
Ganova-Raeva Lilia M, Dimitrova Zoya E, Campo David S, Khudyakov Yury
Abstract excerpt
Detection of genotypes and drug resistance mutations are important molecular tools assisting in clinical management of patients with chronic hepatitis B and C. Together with methods for assessment of genetic heterogeneity and relatedness of viral strains, they form the foundation of molecular surveillance. Currently, all these methods are based mainly on DNA sequencing followed by phylogenetic analysis. Mass...
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