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Article

Rapid quantitation of lamivudine-resistant mutants in lamivudine treated and untreated patients with chronic hepatitis B virus infection.

Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2006

Shi Ming, Yang Zhi-Jun, Wang Rong-Sheng, Zhang Hua, Zhu Yu-Fen, Xu Yong-Ping, Lin Qiu-Ye, Jin Li-Ji

Abstract excerpt

BACKGROUND: Long-term lamivudine treatment induces emergence of lamivudine-resistant hepatitis B virus (HBV) in a significant number of patients with chronic HBV infection. Rapid and quantitative methods to determine the percentage of lamivudine-resistant mutants in total HBV are important during lamivudine therapy. METHODS: We established a quantitative real-time PCR method with selective primers and TaqMan...

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Identifiers

PMID: 16814763
DOI: 10.1016/j.cca.2006.05.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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