Article
HBV mutations associated with lamivudine therapy.
Przeglad epidemiologiczny - 1 Jan 2013
Lapiński Tadeusz Wojciech, Parfieniuk-Kowerda Anna, Trzos Anna, Jaroszewicz Jerzy, Kowalczuk Oksana, Nikliński Jacek, Flisiak Robert
Abstract excerpt
UNLABELLED: Lamivudine (LMV) is still the most commonly used nucleoside analogue in majority of the world. Its administration rapidly leads to resistance associated with mutations in HBV polymerase. THE AIM of the study was to assess the prevalence, nature and the time of LMV resistant variants appearence during a long term therapy. PATIENTS AND METHODS: Study was carried out among 175 chronic hepatitis B...
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