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Article

Rapid detection of lamivudine-resistant hepatitis B virus mutations by PCR-based methods.

The Tohoku journal of experimental medicine - 1 Sept 2006

Chieochansin Thaweesak, Chutinimitkul Salin, Payungporn Sunchai, Theamboonlers Apiradee, Tangkijvanich Pisit, Komolmit Piyawat, Poovorawan Yong

Abstract excerpt

Hepatitis B virus (HBV) is one of the major causes of liver disease worldwide, and chronic HBV infection may progress to cirrhosis and hepatocellular carcinoma. Mutations at the active site of DNA polymerase of HBV, tyrosine-methionine-aspartate-aspartate (YMDD) motif, render infected patients resistant to antiviral drug (Lamivudine) therapy. Hence, sensitive and specific methods aimed at detecting the mutants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16960347
DOI: 10.1620/tjem.210.67

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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