Article
Lamivudine resistance mutations in patients infected with hepatitis B virus genotype D.
World journal of gastroenterology - 7 Dec 2011
Yıldız Orhan, Aygen Bilgehan, Demirtürk Nese, Demirdal Tuna, Inan Dilara, Yıldırmak Taner, Kantürk Arzu, Tütüncü Ediz
Abstract excerpt
AIM: To determine the distribution of viral genotypes for primary or acquired lamivudine resistance. METHODS: A total of 283 patients with chronic hepatitis B virus (HBV) infection (245 patients with chronic hepatitis B and 38 inactive hepatitis B surface antigen carriers) were included in the study. The HBV genotype was determined by using quantitative real-time polymerase chain reaction and sequence analysis,...
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