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Article

MRP2 haplotypes confer differential susceptibility to toxic liver injury.

Pharmacogenetics and genomics - 1 Jun 2007

Choi Ji Ha, Ahn Byung Min, Yi Jihyun, Lee Ji Hyun, Lee Jeong Ho, Nam Soon Woo, Chon Chae Yoon, Han Kwang-Hyub, Ahn Sang Hoon, Jang In-Jin, Cho Joo-Youn, Suh Yousin, Cho Mi-Ook, Lee Jong-Eun, Kim Kyung Hwan, Lee Min Goo

Abstract excerpt

OBJECTIVES: Multidrug resistance protein 2 (MRP2, ABCC2) plays an important role in the biliary clearance of a wide variety of endogenous and exogenous toxic compounds. Therefore, polymorphisms and mutations in the MRP2 gene may affect individual susceptibility to hepatotoxic reactions. METHODS: Associations between genetic variations of MRP2 and toxic hepatitis were investigated using integrated population...

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Identifiers

PMID: 17502832
DOI: 10.1097/01.fpc.0000236337.41799.b3

Genes

ABCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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MRP2 haplotypes confer differential susceptibility to toxic liver injury.PMID 17502832Read ↗

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