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Article

Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.

Expert opinion on drug metabolism & toxicology - 1 Jun 2006

Jedlitschky Gabriele, Hoffmann Ulrich, Kroemer Heyo K

Abstract excerpt

The multi-drug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter playing an important role in detoxification and chemoprotection by transporting a wide range of compounds, especially conjugates of lipophilic substances with glutathione, glucuronate and sulfate, which are collectively known as phase II products of biotransformation. In addition, MRP2 can also transport uncharged compounds...

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Source

Identifiers

PMID: 16863439
DOI: 10.1517/17425255.2.3.351

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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