Article
Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease.
The Journal of nutritional biochemistry - 1 Oct 2009
Sookoian Silvia, Castaño Gustavo, Gianotti Tomas Fernández, Gemma Carolina, Pirola Carlos Jose
Abstract excerpt
AIMS: We hypothesized that ABCC2 gene variants may contribute to susceptibility to nonalcoholic fatty liver disease (NAFLD). Additionally, we tested the hypothesis of a relation between gene variants and disease severity. PATIENTS AND METHODS: The study involved 167 individuals: 109 consecutively presenting unrelated patients with features of NAFLD and different stages of disease severity, and a group of 58...
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