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Article

Autophagy 16-like 1 rs2241880 G allele is associated with Crohn's disease in German children.

Acta paediatrica (Oslo, Norway : 1992) - 1 Nov 2009

Lacher Martin, Schroepf Sebastian, Ballauff Antje, Lohse Peter, von Schweinitz Dietrich, Kappler Roland, Koletzko Sibylle

Abstract excerpt

AIM: Genome-wide association studies have described an association of the ATG16L1 (autophagy 16-like 1) gene rs2241880 variant with Crohn's disease (CD). Therefore, we evaluated this polymorphism in early-onset CD in 152 children and 253 controls and for the first time determined ATG16L1 colonic expression in German CD children. METHODS: Investigation of rs2241880 allele frequencies using a predesigned single...

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PMID: 19659808
DOI: 10.1111/j.1651-2227.2009.01438.x

Genes

NOD2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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