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Article

A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.

Gastroenterology - 1 May 2007

Prescott Natalie J, Fisher Sheila A, Franke Andre, Hampe Jochen, Onnie Clive M, Soars Dianne, Bagnall Richard, Mirza Muddassar M, Sanderson Jeremy, Forbes Alastair, Mansfield John C, Lewis Cathryn M, Schreiber Stefan, Mathew Christopher G

Abstract excerpt

BACKGROUND & AIMS: A genome-wide association scan of nonsynonymous DNA polymorphisms identified association of a threonine-to-alanine substitution (T300A) in the autophagy-related 16-like gene ATG16L1 with Crohn's disease. We investigated this association in independent U.K. cohorts of Crohn's di...

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Identifiers

PMID: 17484864
DOI: 10.1053/j.gastro.2007.03.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17484864-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.PMID 17484864Read ↗

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