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Article

Yra1 is required for S phase entry and affects Dia2 binding to replication origins.

Molecular and cellular biology - 1 Jul 2007

Swaminathan Swarna, Kile Andrew C, MacDonald Elizabeth M, Koepp Deanna M

Abstract excerpt

The Saccharomyces cerevisiae F-box protein Dia2 is important for DNA replication and genomic stability. Using an affinity approach, we identified Yra1, a transcription-coupled mRNA export protein, as a Dia2 interaction partner. We find that yra1 mutants are sensitive to DIA2 expression levels. Like Dia2, Yra1 associates with chromatin and binds replication origins, suggesting that they may function together in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17452447
DOI: 10.1128/MCB.02052-06
PMCID: PMC1951488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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