Characterization of an essential Orc2p-associated factor that plays a role in DNA replication.

doi:10.1128/MCB.16.4.1832

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Article

Characterization of an essential Orc2p-associated factor that plays a role in DNA replication.

Molecular and cellular biology - 1 Apr 1996

Hardy C F

Abstract excerpt

The Saccharomyces cerevisiae Orc2 protein is a subunit of the origin recognition complex, ORC, which binds in a sequence-specific manner to yeast origins of DNA replication. With screens for orc2-1 synthetic lethal mutations and Orc2p two-hybrid interactors, a novel Orc2p-associated factor (Oaf1p...

Topics

Amino Acid Sequence
Cloning, Molecular
DNA Replication
DNA-Binding Proteins
Fungal Proteins
Genes, Fungal
Genes, Synthetic
Molecular Sequence Data
Mutation
Origin Recognition Complex
Plasmids
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Temperature

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