Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.

Molecular and cellular biology - 1 Apr 2002

Mueller Cherie L, Jaehning Judith A

Abstract excerpt

The Saccharomyces cerevisiae Paf1-RNA polymerase II (Pol II) complex is biochemically and functionally distinct from the Srb-mediator form of Pol II holoenzyme and is required for full expression of a subset of genes. In this work we have used tandem affinity purification tags to isolate the Paf1 complex and mass spectrometry to identify additional components. We have established that Ctr9, Rtf1, and Leo1 are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, Affinity
Share to Cyclins
Share to Cysteine Endopeptidases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Macromolecular Substances

Share to Multienzyme Complexes

Share to RNA Polymerase II

Share to Suppression, Genetic

Share to TATA-Box Binding Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 11884586
DOI: 10.1128/MCB.22.7.1971-1980.2002
PMCID: PMC133696

Genes

RTF1
LEO1
CTR9
PAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.PMID 11884586Read ↗

The Paf1 complex has functions independent of actively transcribing RNA polymerase II.Semantic proximity Read ↗

Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism.Semantic proximity Read ↗

Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.Semantic proximity Read ↗

Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA.Semantic proximity Read ↗

A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling.Semantic proximity Read ↗

Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcription.Semantic proximity Read ↗

Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme.Semantic proximity Read ↗

Identification of a role for histone H2B ubiquitylation in noncoding RNA 3'-end formation through mutational analysis of Rtf1 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Synthetic lethal interactions suggest a role for the Saccharomyces cerevisiae Rtf1 protein in transcription elongation.Semantic proximity Read ↗

A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast.Semantic proximity Read ↗

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.Semantic proximity Read ↗

Ctr9, a Key Component of the Paf1 Complex, Affects Proliferation and Terminal Differentiation in the Developing Drosophila Nervous System.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.