Article
The F-box protein Dia2 regulates DNA replication.
Molecular biology of the cell - 1 Apr 2006
Koepp Deanna M, Kile Andrew C, Swaminathan Swarna, Rodriguez-Rivera Veronica
Abstract excerpt
Ubiquitin-mediated proteolysis plays a key role in many pathways inside the cell and is particularly important in regulating cell cycle transitions. SCF (Skp1/Cul1/F-box protein) complexes are modular ubiquitin ligases whose specificity is determined by a substrate-binding F-box protein. Dia2 is a Saccharomyces cerevisiae F-box protein previously described to play a role in invasive growth and pheromone response...
Topics
- DNA Damage
- DNA Replication
- DNA, Fungal
- F-Box Proteins
- Gene Deletion
- Mutation
- Replication Origin
- S Phase
- SKP Cullin F-Box Protein Ligases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins