Article
Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest.
Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 2002
Read Rebecca L, Martinho Rui G, Wang Shao-Win, Carr Antony M, Norbury Chris J
Abstract excerpt
The S-M checkpoint delays mitosis until DNA replication is complete; cells defective in this checkpoint lose viability when DNA replication is inhibited. This inviability can be suppressed in fission yeast by overexpression of Cid1 or the related protein Cid13. Fission yeast contain six cid1/cid13-like genes, whereas budding yeast has just two, TRF4 and TRF5. Trf4 and Trf5 were recently reported to comprise an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
