Article
The conserved Spc7 protein is required for spindle integrity and links kinetochore complexes in fission yeast.
Molecular biology of the cell - 1 Jul 2007
Kerres Anne, Jakopec Visnja, Fleig Ursula
Abstract excerpt
Spc7, a member of the conserved Spc105/KNL-1 family of kinetochore proteins, was identified as an interaction partner of the EB1 homologue Mal3. Spc7 associates with the central centromere region of the chromosome but does not affect transcriptional silencing. Here, we show that Spc7 is required for the integrity of the spindle as well as for targeting of MIND but not of Ndc80 complex components to the...
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