Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intrakinetochore localization and essential functional domains of Drosophila Spc105.

The EMBO journal - 19 Aug 2009

Schittenhelm Ralf B, Chaleckis Romanas, Lehner Christian F

Abstract excerpt

The kinetochore is assembled during mitotic and meiotic divisions within the centromeric region of chromosomes. It is composed of more than eighty different proteins. Spc105 (also designated as Spc7, KNL-1 or Blinkin in different eukaryotes) is a comparatively large kinetochore protein, which can bind to the Mis12/MIND and Ndc80 complexes and to the spindle assembly checkpoint components Bub1 and BubR1. Our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantigens
Share to Chromosomal Proteins, Non-Histone
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Kinetochores

Share to Mitosis

Share to Repetitive Sequences, Amino Acid

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 19590494
DOI: 10.1038/emboj.2009.188
PMCID: PMC2735171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intrakinetochore localization and essential functional domains of Drosophila Spc105.PMID 19590494Read ↗

Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.Semantic proximity Read ↗

The conserved Spc7 protein is required for spindle integrity and links kinetochore complexes in fission yeast.Semantic proximity Read ↗

Drosophila Mis12 complex acts as a single functional unit essential for anaphase chromosome movement and a robust spindle assembly checkpoint.Semantic proximity Read ↗

Concurrent duplication of the Cid and Cenp-C genes in the Drosophila subgenus with signatures of subfunctionalization and male germline-biased expressionSemantic proximity Read ↗

Homotetrameric form of Cin8p, a Saccharomyces cerevisiae kinesin-5 motor, is essential for its in vivo function.Semantic proximity Read ↗

The Spc105/Kre28 complex promotes mitotic error correction by outer kinetochore recruitment of Ipl1/Sli15.Semantic proximity Read ↗

The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association.Semantic proximity Read ↗

The CLIP-170 orthologue Bik1p and positioning the mitotic spindle in yeast.Semantic proximity Read ↗

Knl1 participates in spindle assembly checkpoint signaling in maize.Semantic proximity Read ↗

Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation.Semantic proximity Read ↗

Sos7, an essential component of the conserved Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a new family of fungal kinetochore proteins.Semantic proximity Read ↗

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.