Article
Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae.
The EMBO journal - 21 Apr 2004
Crotti Luciana B, Basrai Munira A
Abstract excerpt
The kinetochore (centromeric DNA and associated proteins) mediates the attachment of chromosomes to the mitotic spindle apparatus and is required for faithful chromosome transmission. We established that evolutionarily conserved Saccharomyces cerevisiae SPT4, previously identified in genetic screens for defects in chromosome transmission fidelity (ctf), encodes a new structural component of specialized chromatin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
