Article
[C677T polymorphism of the methylentetrahydrofolate reductase gene in mothers of children affected with neural tube defects].
Investigacion clinica - 1 Sept 2015
Morales de Machín Alisandra, Méndez Karile, Solís Ernesto, Borjas de Borjas Lisbeth, Bracho Ana, Hernández María Luisa, Negrón Aimara, Delgado Wilmer, Sánchez Yanira
Abstract excerpt
Neural tube defects (NTD) are the most common congenital anomalies of the central nervous system, with a multifactorial pattern of inheritance, presumably involving the interaction of several genetic and environmental factors. The methylenetetrahydrofolate reductase (MTHFR) gene 677C>T polymorphi...
Topics
- Adolescent
- Adult
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Infant, Newborn
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Neural Tube Defects
- Polymerase Chain Reaction