Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin resistance-related genes and advanced left-sided colorectal adenoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2007

Gunter Marc J, Hayes Richard B, Chatterjee Nilanjan, Yeager Meredith, Welch Robert, Schoen Robert E, Yakochi Lance, Schatzkin Arthur, Peters Ulrike

Abstract excerpt

BACKGROUND: Insulin resistance has been linked with colorectal neoplasia through a number of mechanistic and observational studies. Allelic variants of genes encoding components of the insulin pathway, including insulin (INS), insulin receptor (INSR), and insulin receptor substrate-1 and insulin receptor substrate-2 (IRS1 and IRS2) have been associated with hyperinsulinemia and insulin resistance and may,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adenomatous Polyps

Share to Case-Control Studies

Share to Colorectal Neoplasms

Share to Insulin Resistance

Share to Receptor, Insulin

Share to Risk Factors

Source

Identifiers

PMID: 17416760
DOI: 10.1158/1055-9965.EPI-06-0849

Genes

INSR
INS
IRS1
IRS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin resistance-related genes and advanced left-sided colorectal adenoma.PMID 17416760Read ↗

Genetic variation in insulin pathway genes and distal colorectal adenoma risk.Semantic proximity Read ↗

Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer.Semantic proximity Read ↗

Insulin pathway related genes and risk of colorectal cancer: INSR promoter polymorphism shows a protective effect.Semantic proximity Read ↗

Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk.Semantic proximity Read ↗

An exon variant in insulin receptor gene is associated with susceptibility to colorectal cancer in women.Semantic proximity Read ↗

Is there an association between variants in candidate insulin pathway genes IGF-I, IGFBP-3, INSR, and IRS2 and risk of colorectal cancer in the Iranian population?Semantic proximity Read ↗

Lack of association between insulin receptor substrate2 rs1805097 polymorphism and the risk of colorectal and breast cancer: a meta-analysis.Semantic proximity Read ↗

Genetic variants and traits related to insulin-like growth factor-I and insulin resistance and their interaction with lifestyles on postmenopausal colorectal cancer risk.Semantic proximity Read ↗

Genes in the insulin and insulin-like growth factor pathway and odds of metachronous colorectal neoplasia.Semantic proximity Read ↗

Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study.Semantic proximity Read ↗

Insulin receptor variants and obesity-related cancers in the Framingham Heart Study.Semantic proximity Read ↗

Blood lipids and colorectal polyps: testing an etiologic hypothesis using phenotypic measurements and Mendelian randomization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.