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Article

An exon variant in insulin receptor gene is associated with susceptibility to colorectal cancer in women.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2015

Mahmoudi Touraj, Majidzadeh-A Keivan, Karimi Khatoon, Karimi Negar, Farahani Hamid, Dabiri Reza, Nobakht Hossein, Dolatmoradi Hesamodin, Arkani Maral, Zali Mohammad Reza

Abstract excerpt

Given the role of insulin resistance in colorectal cancer (CRC), we explored whether genetic variants in insulin (INS), insulin receptor (INSR), insulin receptor substrate 1 (IRS1), insulin receptor substrate 2 (IRS2), insulin-like growth factor 1 (IGF1), and insulin-like growth factor binding protein 3 (IGFBP3) genes were associated with CRC risk. A total of 600 subjects, including 261 cases with CRC and 339...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25557790
DOI: 10.1007/s13277-014-3010-x

Genes

INSR
IGF1
IGFBP3
INS
IRS1
IRS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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