Article
Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk.
Cancer causes & control : CCC - 1 Feb 2014
Ochs-Balcom Heather M, Vaughn Caila B, Nie Jing, Chen Zhengyi, Thompson Cheryl L, Parekh Niyati, Tracy Russell, Li Li
Abstract excerpt
PURPOSE: Insulin resistance is believed to play an important role in the link between energy imbalance and colon carcinogenesis. Emerging evidence suggests that there are substantial racial differences in genetic and anthropometric influences on insulin-like growth factors (IGFs); however, few studies have examined racial differences in the associations of IGFs and colorectal adenoma, precursor lesions of colon...
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