Article
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.
Nature genetics - 1 May 2007
Yeager Meredith, Orr Nick, Hayes Richard B, Jacobs Kevin B, Kraft Peter, Wacholder Sholom, Minichiello Mark J, Fearnhead Paul, Yu Kai, Chatterjee Nilanjan, Wang Zhaoming, Welch Robert, Staats Brian J, Calle Eugenia E, Feigelson Heather Spencer, Thun Michael J, Rodriguez Carmen, Albanes Demetrius, Virtamo Jarmo, Weinstein Stephanie, Schumacher Fredrick R, Giovannucci Edward, Willett Walter C, Cancel-Tassin Geraldine, Cussenot Olivier, Valeri Antoine, Andriole Gerald L, Gelmann Edward P, Tucker Margaret, Gerhard Daniela S, Fraumeni Joseph F, Hoover Robert, Hunter David J, Chanock Stephen J, Thomas Gilles
Abstract excerpt
Recently, common variants on human chromosome 8q24 were found to be associated with prostate cancer risk. While conducting a genome-wide association study in the Cancer Genetic Markers of Susceptibility project with 550,000 SNPs in a nested case-control study (1,172 cases and 1,157 controls of European origin), we identified a new association at 8q24 with an independent effect on prostate cancer susceptibility....
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