Article
A common 8q24 variant in prostate and breast cancer from a large nested case-control study.
Cancer research - 1 Apr 2007
Schumacher Fredrick R, Feigelson Heather Spencer, Cox David G, Haiman Christopher A, Albanes Demetrius, Buring Julie, Calle Eugenia E, Chanock Stephen J, Colditz Graham A, Diver W Ryan, Dunning Alison M, Freedman Matthew L, Gaziano John M, Giovannucci Edward, Hankinson Sue E, Hayes Richard B, Henderson Brian E, Hoover Robert N, Kaaks Rudolf, Key Timothy, Kolonel Laurence N, Kraft Peter, Le Marchand Loic, Ma Jing, Pike Malcolm C, Riboli Elio, Stampfer Meir J, Stram Daniel O, Thomas Gilles, Thun Michael J, Travis Ruth, Virtamo Jarmo, Andriole Gerald, Gelmann Edward, Willett Walter C, Hunter David J
Abstract excerpt
Two recent studies independently identified polymorphisms in the 8q24 region, including a single nucleotide polymorphism (rs1447295), strongly associated with prostate cancer risk. Here, we replicate the overall association in a large nested case-control study from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium using 6,637 prostate cancer cases and 7,361 matched controls. We also...
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