Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.

doi:10.1007/s00439-016-1690-6

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Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.

Human genetics - 1 Aug 2016

Teerlink Craig C, Leongamornlert Daniel, Dadaev Tokhir, Thomas Alun, Farnham James, Stephenson Robert A, Riska Shaun, McDonnell Shannon K, Schaid Daniel J, Catalona William J, Zheng S Lilly, Cooney Kathleen A, Ray Anna M, Zuhlke Kimberly A, Lange Ethan M, Giles Graham G, Southey Melissa C, Fitzgerald Liesel M, Rinckleb Antje, Luedeke Manuel, Maier Christiane, Stanford Janet L, Ostrander Elaine A, Kaikkonen Elina M, Sipeky Csilla, Tammela Teuvo, Schleutker Johanna, Wiley Kathleen E, Isaacs Sarah D, Walsh Patrick C, Isaacs William B, Xu Jianfeng, Cancel-Tassin Geraldine, Cussenot Olivier, Mandal Diptasri, Laurie Cecelia, Laurie Cathy, Thibodeau Stephen N, Eeles Rosalind A, Kote-Jarai Zsofia, Cannon-Albright Lisa

Abstract excerpt

Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer Genetics (ICPCG) has now performed a GWAS of 2511 (unrelated) familial prostate cancer cases and 1382 unaffected controls from 12 member sites. All samples were genotyped on the Illumina 5M+exome...

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PMID: 27262462
DOI: 10.1007/s00439-016-1690-6
PMCID: PMC5020907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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