Article
Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2008
Salinas Claudia A, Kwon Erika, Carlson Christopher S, Koopmeiners Joseph S, Feng Ziding, Karyadi Danielle M, Ostrander Elaine A, Stanford Janet L
Abstract excerpt
Recently, the 8q24 region has been identified as a prostate cancer susceptibility locus in a genome-wide scan of prostate cancer families in Iceland and an admixture scan of African Americans. Further investigations of variants at 8q24 have shown the existence of additional single nucleotide polymorphisms (SNPs) that enhance prostate cancer risk, suggesting the possibility of multiple regions harboring variants...
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