Article
Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.
Journal of the National Cancer Institute - 1 Jul 2016
Han Ying, Rand Kristin A, Hazelett Dennis J, Ingles Sue A, Kittles Rick A, Strom Sara S, Rybicki Benjamin A, Nemesure Barbara, Isaacs William B, Stanford Janet L, Zheng Wei, Schumacher Fredrick R, Berndt Sonja I, Wang Zhaoming, Xu Jianfeng, Rohland Nadin, Reich David, Tandon Arti, Pasaniuc Bogdan, Allen Alex, Quinque Dominique, Mallick Swapan, Notani Dimple, Rosenfeld Michael G, Jayani Ranveer Singh, Kolb Suzanne, Gapstur Susan M, Stevens Victoria L, Pettaway Curtis A, Yeboah Edward D, Tettey Yao, Biritwum Richard B, Adjei Andrew A, Tay Evelyn, Truelove Ann, Niwa Shelley, Chokkalingam Anand P, John Esther M, Murphy Adam B, Signorello Lisa B, Carpten John, Leske M Cristina, Wu Suh-Yuh, Hennis Anslem J M, Neslund-Dudas Christine, Hsing Ann W, Chu Lisa, Goodman Phyllis J, Klein Eric A, Zheng S Lilly, Witte John S, Casey Graham, Lubwama Alex, Pooler Loreall C, Sheng Xin, Coetzee Gerhard A, Cook Michael B, Chanock Stephen J, Stram Daniel O, Watya Stephen, Blot William J, Conti David V, Henderson Brian E, Haiman Christopher A
Abstract excerpt
The 8q24 region harbors multiple risk variants for distinct cancers, including >8 for prostate cancer. In this study, we conducted fine mapping of the 8q24 risk region (127.8-128.8Mb) in search of novel associations with common and rare variation in 4853 prostate cancer case patients and 4678 control subjects of African ancestry. All statistical tests were two-sided. We identified three independent associations...
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