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Article

Novel sfi1 alleles uncover additional functions for Sfi1p in bipolar spindle assembly and function.

Molecular biology of the cell - 1 Jun 2007

Anderson Victoria E, Prudden John, Prochnik Simon, Giddings Thomas H, Hardwick Kevin G

Abstract excerpt

A variety of spindle and kinetochore defects have been shown to induce a mitotic delay through activation of the spindle checkpoint. With the aim of identifying novel mitotic defects we carried out a mad1 synthetic lethal screen in budding yeast. In this screen, four novel alleles of sfi1 were isolated. SFI1 is an essential gene, previously identified through its interaction with centrin/CDC31 and shown to be...

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Identifiers

PMID: 17392514
DOI: 10.1091/mbc.e06-10-0918
PMCID: PMC1877113

Genes

SFI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel sfi1 alleles uncover additional functions for Sfi1p in bipolar spindle assembly and function.PMID 17392514Read ↗

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