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Article

The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans.

Current biology : CB - 23 Dec 2002

Kitagawa Risa, Law Elaine, Tang Lois, Rose Ann M

Abstract excerpt

Accurate chromosome segregation is achieved by a series of highly regulated processes that culminate in the metaphase-to-anaphase transition of the cell cycle. In the budding yeast Saccharomyces cerevisiae, the degradation of the securin protein Pds1 reverses the binding and inhibition of the separase protein Esp1. Esp1 cleaves Scc1. That cleavage promotes the dissociation of the cohesin complex from the...

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Identifiers

PMID: 12498686
DOI: 10.1016/s0960-9822(02)01392-1

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APC
CDC20

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The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans.PMID 12498686Read ↗

The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae.Semantic proximity Read ↗

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