Article
The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p.
Molecular biology of the cell - 1 Apr 2006
Araki Yasuhiro, Lau Corine K, Maekawa Hiromi, Jaspersen Sue L, Giddings Thomas H, Schiebel Elmar, Winey Mark
Abstract excerpt
The spindle pole body (SPB) in Saccharomyces cerevisiae functions to nucleate and organize spindle microtubules, and it is embedded in the nuclear envelope throughout the yeast life cycle. However, the mechanism of membrane insertion of the SPB has not been elucidated. Ndc1p is an integral membrane protein that localizes to SPBs, and it is required for insertion of the SPB into the nuclear envelope during SPB...
Topics
- Alleles
- Calmodulin-Binding Proteins
- Carrier Proteins
- Cell Cycle
- Cell Cycle Proteins
- Cell Membrane
- Cytoskeletal Proteins
- DNA-Binding Proteins
- Genes, Essential
- Genes, Fungal