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Article

Yeast Dam1p is required to maintain spindle integrity during mitosis and interacts with the Mps1p kinase.

Molecular biology of the cell - 1 Jul 1999

Jones M H, Bachant J B, Castillo A R, Giddings T H, Winey M

Abstract excerpt

We have identified a mutant allele of the DAM1 gene in a screen for mutations that are lethal in combination with the mps1-1 mutation. MPS1 encodes an essential protein kinase that is required for duplication of the spindle pole body and for the spindle assembly checkpoint. Mutations in six different genes were found to be lethal in combination with mps1-1, of which only DAM1 was novel. The remaining genes encode...

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Identifiers

PMID: 10397771
DOI: 10.1091/mbc.10.7.2377
PMCID: PMC25456

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Source receipt: pubmed, retrieved 7 Sept 2026.

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